Publications produced by Gortec

These publications are arranged in descending chronological order.


Radiother Oncol. 2020 Mar 27;147:30-39. doi: 10.1016/j.radonc.2020.03.006

Proton therapy for head and neck squamous cell carcinomas: A review of the physical and clinical challenges

Arnaud Beddok, Anthony Vela, Valentin Calugaru, Thomas Tessonnier, Jiri Kubes, Pauline Dutheil, Anais Gerard, Marie Vidal, Farid Goudjil, Carmen Florescu, Emmanuel Kammerer, Karen Benezery, Joel Herault, Philip Poortmans, Jean Bourhis, Juliette Thariat, on behalf of the GORTEC, the 3 French proton centers

Click here to download the full version in .pdf format

[ See full publication ]


2017-01 REACH

Barcelona 2019 ESMO Congress - Poster

Avelumab-cetuximab-radiotherapy versus standards of care in locally advanced squamous cell carcinoma of the Head and Neck: Safety phase of the randomized phase III trial GORTEC 2017-01 REACH
Publication PDF

Y Tao, A Auperin, X Sun, C Sire, L Martin, A Coutte, C Lafond, J Miroir, X Liem, F Rolland, A Maillard, N Colin-Barailhou, C Michel, J Thariat, J Guigay, J Bourhis


ELAN FIT ELAN UNFIT

Barcelona 2019 ESMO Congress - Oral Presentation

Personalized treatment according to geriatric assessment in 1st line recurrent and/or metastatic (r/m) Head and Neck Squamous Cell Cancer (HNSCC) patients aged 70 or over.
Publication PDF

J. Guigay, A. Auperin, C. Mertens, C. Even, L. Geoffrois, D. Cupissol, F. Rolland, C. Sire, J. Fayette, F. Peyrade, E. Blot, P. Debourdeau, L. Bozec Le Moal, O. Capitain, Y. Pointreau, C. Brard, C. Michel, D. Schwob, C. Ortholan, H. Le Caer


Front Oncol. 2019 May 31;9:419. doi: 10.3389/fonc.2019.00419. eCollection 2019.

Laryngeal Preservation Strategies in Locally Advanced Laryngeal and Hypopharyngeal Cancers.

Argiris A, Lefebvre JL.

[ See publication ]


Curr Opin Oncol. 2019 May;31(3):152-159. doi: 10.1097/CCO.0000000000000526.

Treatment of inoperable elderly head and neck cancer patients.

Guigay J, Le Caer H, Ortholan C, Aupérin A, Michel C, Mertens C.Guigay J, Le Caer H, Ortholan C, Aupérin A, Michel C, Mertens C.

[ See publication ]


Cancer Radiother. 2019 Sep;23(5):439-448. doi: 10.1016/j.canrad.2019.05.015. Epub 2019 Jul 26.

Proton therapy for head and neck squamous cell carcinomas : From physics to clinic

Beddok A, Vela A, Calugaru V, Tessonnier T, Kubes J, Dutheil P, Gérard A, Vidal M, Goudjil F, Florescu C, Kammerer E, Bénézery K, Hérault J, Bourhis J, Thariat J; Gortec et de trois centres français.

[ See publication ]


Radiother Oncol. 2019 Feb

Practical clinical guidelines for contouring the trigeminal nerve (V) and its branches in head and neck cancers.

Biau J, Dunet V, Lapeyre M, Simon C, Ozsahin M, Grégoire V, Bourhis J.

[ See publication ]


GORTEC 2007-01

Randomized Trial of Concomitant Chemotherapy in Patients With Locally Advanced HNSCC Treated by Radiotherapy-erbitux (2007-01)
Publication PDF

Multicenter, randomized, phase III trial evaluating the benefit of concomitant chemotherapy in patients receiving radiotherapy - Erbitux for locally advanced carcinoma of the upper aerodigestive tract <= N2a.
Coordinator : Prof. BOURHIS
Start date : 2008
Number of patients    406

Access the Clinical Trials link


GORTEC 2007-02

Chemoradiotherapy HNSCC, Randomized Study, Docetaxel,Cisplatin, 5FU,Erbitux. (2007/02)

Publication PDF

Randomized, multicenter Phase III study, comparing an induction chemotherapy with TPF followed by radiotherapy and concurrent Erbitux® versus chemoradiotherapy for patients with inoperable locally advanced squamous cell carcinoma of the upper aerodigestive tract >=N2b
Coordinator : Dr GEOFFROIS
Start date : 2009
Nb Patients    360

Access the Clinical Trials link


J Clin Oncol. 2018 Jul 17

Induction Chemotherapy Followed by Cetuximab Radiotherapy Is Not Superior to Concurrent Chemoradiotherapy for Head and Neck Carcinomas: Results of the GORTEC 2007-02 Phase III Randomized Trial.

Geoffrois L, Martin L, De Raucourt D, Sun XS, Tao Y, Maingon P, Buffet J, Pointreau Y, Sire C, Tuchais C, Babin E, Coutte A, Rolland F, Kaminsky MC, Alfonsi M, Lapeyre M, Saliou M, Lafond C, Jadaud E, Gery B, Zawadi A, Tourani JM, Khoury C, Henry AR, Hasbini A, Guichard F, Borel C, Meert N, Guillet P, Calais MH, Garaud P, Bourhis J.

[ See publication ]


J Clin Oncol. 2018 Jun 7

Improved Outcome by Adding Concurrent Chemotherapy to Cetuximab and Radiotherapy for Locally Advanced Head and Neck Carcinomas: Results of the GORTEC 2007-01 Phase III Randomized Trial.

Tao Y, Auperin A, Sire C, Martin L, Khoury C, Maingon P, Bardet E, Kaminsky MC, Lapeyre M, Chatellier T, Alfonsi M, Pointreau Y, Jadaud E, Géry B, Zawadi A, Tourani JM, Laguerre B, Coutte A, Racadot S, Hasbini A, Malaurie E, Borel C, Meert N, Cornely A, Ollivier N, Casiraghi O, Sun XS, Bourhis J.

[ See publication ]


Future Oncol. 2018 Apr

Approach to oligometastatic disease in head and neck cancer, on behalf of the GORTEC.

Sun XS, Michel C, Babin E, De Raucourt D, Péchery A, Gherga E, Géry B, Florescu C, Bourhis J, Thariat J.

[ See publication ]


Int J Radiat Oncol Biol Phys. 2017 Nov 1

Multicenter Randomized Double-Blind, Placebo-Controlled Trial GORTEC (Groupe Oncologie Radiotherapie Tete et Cou) 2009-01 Evaluating the Effect of the Regenerating Agent on Radiodermatitis of Head and Neck Cancer Patients.

Tao Y, Auperin A, Sire C, Martin M, Saliou MG, Bardet E, Sun XS, Chatellier T, Morand C, Cornely A, Angokai M, Di Rito A, Kichenin K, Blanchard P, D'Onofrio I, Bourhis J.

[ See publication ]


Ann Oncol. 2018 Mar 1

A randomized trial of induction docetaxel-cisplatin-5FU followed by concomitant cisplatin-RT versus concomitant cisplatin-RT in nasopharyngeal carcinoma (GORTEC 2006-02).

Frikha M, Auperin A, Tao Y, Elloumi F, Toumi N, Blanchard P, Lang P, Sun S, Racadot S, Thariat J, Alfonsi M, Tuchais C, Cornely A, Moussa A, Guigay J, Daoud J, Bourhis J; GORTEC.

[ See publication ]


Radiother Oncol. 2018 Jan

Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines.

Grégoire V, Evans M, Le QT, Bourhis J, Budach V, Chen A, Eisbruch A, Feng M, Giralt J, Gupta T, Hamoir M, Helito JK, Hu C, Hunter K, Johansen J, Kaanders J, Laskar SG, Lee A, Maingon P, Mäkitie A, Micciche' F, Nicolai P, O'Sullivan B, Poitevin A, Porceddu S, Składowski K, Tribius S, Waldron J, Wee J, Yao M, Yom SS, Zimmermann F, Grau C.

[ See publication ]


Cancer Radiother. 2017 Oct

[Description of the GORTEC 2017-03 study: Postoperative stereotactic radiotherapy for early stage oropharyngeal and oral cavity cancer with high risk margin (PHRC-K-16-164)].

Biau J, Miroir J, Millardet C, Saroul N, Pham-Dang N, Racadot S, Huguet F, Kwiatkowski F, Pereira B, Bourhis J, Lapeyre M.

[ See publication ]


Oral Oncol. 2017 Aug

Very accelerated radiotherapy or concurrent chemoradiotherapy for N3 head and neck squamous cell carcinoma: Pooled analysis of two GORTEC randomized trials.

Tao Y, Aupérin A, Graff P, Lapeyre M, Grégoire V, Maingon P, Geoffrois L, Verrelle P, Calais G, Gery B, Martin L, Alfonsi M, Deprez P, Bardet E, Pignon T, Rives M, Sire C, Bourhis J.

[ See publication ]


Oral Oncol. 2017 May

Long-term response in patient with recurrent oropharyngeal carcinoma treated with cetuximab, docetaxel and cisplatin (TPEx) as first-line treatment followed by cetuximab maintenance.

Guigay J, Even C, Mayache-Badis L, Debbah M, Saada-Bouzid E, Tao Y, Deschamps F, Janot F, Lezghed N, Michel C.

[ See publication ]


Radiother Oncol. 2015 Oct

CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.

Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA.

[ See publication ]


Ann Oncol. 2015 Sep

Cetuximab, docetaxel, and cisplatin as first-line treatment in patients with recurrent or metastatic head and neck squamous cell carcinoma: a multicenter, phase II GORTEC study.

Guigay J, Fayette J, Dillies AF, Sire C, Kerger JN, Tennevet I, Machiels JP, Zanetta S, Pointreau Y, Bozec Le Moal L, Henry S, Schilf A, Bourhis J.

[ See publication ]


Bull Cancer. 2014 May 1

[Quality criteria in radiotherapy for head and neck cancers under the aegis of Head and Neck Intergroup].

Tao Y, Vintonenko N, Garcia R, Marchesi V, Tomsej M, Bardet E, Bourhis J.

[ See publication ]


Bull Cancer. 2013 Oct

[Advances in head and neck cancers on behalf of the French Intergroup ORL and GORTEC].

Thariat J, Jegoux F, Pointreau Y, Fayette J, Boisselier P, Blanchard P, Alfonsi M, Aupérin A, Bardet E, Bensadoun RJ, Garaud P, Geoffrois L, Graff P, Guigay J, Janot F, Lapeyre M, Lefebvre JL, Martin L, Racadot S, Rolland F, Sire C, Tao Y, Tuchais C, Chibaudel B, Girard-Calais MH, Cornely A, Vintonenko N, Calais G, De Raucourt D, Lacau Saint-Guily J, Bourhis J.

[ See publication ]


J Clin Oncol. 2013 Mar

Induction chemotherapy followed by either chemoradiotherapy or bioradiotherapy for larynx preservation: the TREMPLIN randomized phase II study.

Lefebvre JL1, Pointreau Y, Rolland F, Alfonsi M, Baudoux A, Sire C, de Raucourt D, Malard O, Degardin M, Tuchais C, Blot E, Rives M, Reyt E, Tourani JM, Geoffrois L, Peyrade F, Guichard F, Chevalier D, Babin E, Lang P, Janot F, Calais G, Garaud P, Bardet E.

[ See full publication ]


Radiat Oncol. 2013 Feb

Phase I trial of oral etoposide in combination with radiotherapy in head and neck squamous cell carcinoma - GORTEC 2004-02

Tao Y, Bardet E, Rosine D, Rolland F, Bompas E, Daly-Schveitzer N, Lusinchi A, Bourhis J.

[ See full publication ]


Radiother Oncol. 2012 Apr

Intensity-modulated radiotherapy in head and neck cancer: results of the prospective study GORTEC 2004-03.

Toledano I, Graff P, Serre A, Boisselier P, Bensadoun RJ, Ortholan C, Pommier P, Racadot S, Calais G, Alfonsi M, Favrel V, Giraud P, Lapeyre M.

[ See publication ]


Lancet Oncol. 2012 Apr

Absent benefit of accelerated concomitant chemoradiotherapy (GORTEC 99-02)  

Bourhis J, Tao YG, Blanchard P, Sire C, Aupérin A .

[ See full publication ]


The Lancet Oncology. 2012 Feb

Concomitant chemoradiotherapy versus acceleration of radiotherapy with or without concomitant chemotherapy in locally advanced head and neck carcinoma (GORTEC 99-02): an open-label phase 3 randomised trial

Prof Jean Bourhis, Christian Sire, Pierre Graff, Prof Vincent Grégoire,Prof Philippe Maingon,Prof Gilles Calais, Bernard Gery, Laurent Martin, Marc Alfonsi, Patrick Desprez, Thierry Pignon, Etienne Bardet, Michel Rives, Lionel Geoffrois, Prof Nicolas Daly-Schveitzer, Sok Sen, Claude Tuchais, Olivier Dupuis, Stéphane Guerif, Michel Lapeyre, Véronique Favrel, Prof Marc Hamoir, Antoine Lusinchi, Stéphane Temam, Antonella Pinna, BScYun Gan Tao, Pierre Blanchard, Anne Aupérin

[ See full publication (The lancet) ]

[ See full publication (pubmed)]


Radiother Oncol. 2011 Jul

Accelerated radiotherapy and concomitant high dose chemotherapy in non resectable stage IV locally advanced HNSCC: results of a GORTEC randomized trial.

Bourhis J, Lapeyre M, Tortochaux J, Lusinchi A, Etessami A, Ducourtieux M, Geoffrois L, Domenge C, Verrelle P, Wibault P, Janot F, Temam S, Blanchard P, Tao YG, Auperin A. Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France

Click here to download the full version in .pdf format

[ See full publication ]


Radiother Oncol. 2011 Jul

Randomized phase III trial (GORTEC 98-03) comparing re-irradiation plus chemotherapy versus methotrexate in patients with recurrent or a second primary head and neck squamous cell carcinoma, treated with a palliative intent.

Tortochaux J, Tao Y, Tournay E, Lapeyre M, Lesaunier F, Bardet E, Janot F, Lusinchi A, Benhamou E, Bontemps P, Maingon P, Calais G, Daly-Schveitzer N, Verrelle P, Bourhis J.

Click here to download the full version in .pdf format

[ See full publication ]


Radiother Oncol. 2011 Jan

A phase I trial combining oral cisplatin (CP Ethypharm) with radiotherapy in patients with locally advanced head and neck squamous cell carcinoma.

Tao Y, Rezaï K, Brain E, Etessami A, Lusinchi A, Temam S, Urien S, Van ML, Vauzelle-Kervroedan F, Lokiec F, Daly-Schveitzer N, Bourhis J.

[ See full publication ]


J Clin Oncol. 2010 Nov 29

Subcutaneous Compared With Intravenous Administration of Amifostine in Patients With Head and Neck Cancer Receiving Radiotherapy: Final Results of the GORTEC 2000-02 Phase III Randomized Trial.

Bardet E, Martin L, Calais G, Alfonsi M, Feham NE, Tuchais C, Boisselier P, Dessard-Diana B, Seng SH, Garaud P, Aupérin A, Bourhis J.

 [ See full publication ]


J Clin Oncol. - 2010 Jan 1

Phase II study of sunitinib in recurrent or metastatic squamous cell carcinoma of the head and neck: GORTEC 2006-01.

Machiels JP, Henry S, Zanetta S, Kaminsky MC, Michoux N, Rommel D, Schmitz S, Bompas E, Dillies AF, Faivre S, Moxhon A, Duprez T, Guigay J.
Medical Oncology Unit, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc

[ See full publication ]


Int J Radiat Oncol Biol Phys. - 2009 Apr 20

TPF : a rational choice for larynx preservation ?

Calais G.

[ See full publication ]


Concomitant Chemoradiotherapy Using Carboplatin, Tegafur-Uracil and Leucovorin for Stage III and IV Head-and-Neck Cancer: Results of GORTEC Phase II Study.

Fesneau M, Pointreau Y, Chapet S, Martin L, Pommier P, Alfonsi M, Laguerre B, Feham N, Berger C, Garaud P, Calais G.
Department of Radiation Oncology, Henry Kaplan Center, Tours, France.


Head Neck - 2009 Apr

Larynx preservation clinical trial design: key issues and recommendations--a consensus panel summary.
Ang K, Bardet E, Barry B, Bernier J, Bourhis J, Budach V, Calais G, Conley B, Forastiere A, Knecht R, Langendijk J, Lefebvre JL, Leemans R, Licitra L, Posner M, de Raucourt D, Rolland F, Temam S, Vermorken JB, Vokes E, Weber RS, Wolf G.
Département de Cancérologie Cervico-Faciale, Centre Oscar Lambret, Lille, France


J Natl Cancer Inst. 2009 Apr 1

Randomized trial of induction chemotherapy with cisplatin and 5-fluorouracil with or without docetaxel for larynx preservation.

Pointreau Y, Garaud P, Chapet S, Sire C, Tuchais C, Tortochaux J, Faivre S, Guerrif S, Alfonsi M, Calais G.


J Clin Oncol - 2008 Dec 1

Randomized trial of postoperative reirradiation combined with chemotherapy after salvage surgery compared with salvage surgery alone in head and neck carcinoma. 
Janot F, de Raucourt D, Benhamou E, Ferron C, Dolivet G, Bensadoun RJ, Hamoir M, Géry B, Julieron M, Castaing M, Bardet E, Grégoire V, Bourhis J. 
Institut Gustave-Roussy, 39 rue Camille Desmoulins, Villejuif, France


Rev Prat. - 2006 Oct 15

Non surgical treatment approach for head and neck cancer
Pointreau Y, Calais G.
Clinique d'oncologie radiothérapie, centre de cancérologie H.S. Kaplan, hôpital Bretonneau, CHRU de Tours, 37044 Tours.

J Clin Oncol. - 2006 Jun 20

Phase III randomized trial of very accelerated radiation therapy compared with conventional radiation therapy in squamous cell head and neck cancer: a GORTEC trial 
Bourhis J, Lapeyre M, Tortochaux J, Rives M, Aghili M, Bourdin S, Lesaunier F, Benassi T, Lemanski C, Geoffrois L, Lusinchi A, Verrelle P, Bardet E, Julieron M, Wibault P, Luboinski M, Benhamou E. 
Institut Gustave Roussy, Radiation Oncology, Head and Neck Statistics Department, Villejuif, France


Int J Radiat Oncol Biol Phys. - 2006 Mar 15

French multicenter phase III randomized study testing concurrent twice-a-day radiotherapy and cisplatin/5-fluorouracil chemotherapy (BiRCF) in unresectable pharyngeal carcinoma: Results at 2 years (FNCLCC-GORTEC). 
Bensadoun RJ, Bénézery K, Dassonville O, Magné N, Poissonnet G, Ramaïoli A, Lemanski C, Bourdin S, Tortochaux J, Peyrade F, Marcy PY, Chamorey E, Vallicioni J, Seng H, Alzieu C, Géry B, Chauvel P, Schneider M, Santini J, Demard F, Calais G.
Department of Radiation Oncology, Centre Antoine Lacassagne, Nice, France


Cancer Radiother. - 2005 Jun

Propositions for the selection and the delineation of peritumoral microscopic disease volumes in oral cavity and oropharyngeal cancers (lymph nodes excluded)
Bensadoun RJ, Bénézery K, Dassonville O, Magné N, Poissonnet G, Ramaïoli A, Lemanski C, Bourdin S, Tortochaux J, Peyrade F, Marcy PY, Chamorey E, Vallicioni J, Seng H, Alzieu C, Géry B, Chauvel P, Schneider M, Santini J, Demard F, Calais G., GORTEC 
Département de radiothérapie, centre Alexis-Vautrin, avenue de Bourgogne, 54511 Vandoeuvre-Lès-Nancy, France


Cancer Radiother. - 2005 Feb

Larynx preservation, state of the art
Lefebvre JL, Calais G. 
Département de cancérologie cervicofaciale, centre Oscar-Lambret, 3, rue Combemale, 59020 Lille cedex, France.


Cancer Radiother. 2005 Jun;9(4):261-70. Epub 2005 Apr 25.

Propositions for the selection and the delineation of peritumoral microscopic disease volumes in oral cavity and oropharyngeal cancers (lymph nodes excluded)
Lapeyre M, Henrot P, Alfonsi M, Bardet E, Bensadoun RJ, Dolivet G, Favrel V, Gallocher O, Giraud P, Graff P, Guerif S, Lagarde P, Lartigau E, Marchesi V, Pommier P, Rives M, Tortochaux J, Toussaint B, Verrelle P, Bourhis J, Calais G; Groupe Oncologie Radiothérapie Tête et Cou.
Department of Radiotherapy, centre Alexis-Vautrin, avenue de Bourgogne, 54511 Vandoeuvre-Lès-Nancy, France. m.lapeyre[@]nancy.fnclcc.fr


Semin Oncol. - 2004 Dec

Concomitant radiochemotherapy or accelerated radiotherapy: analysis of two randomized trials of the French Head and Neck Cancer Group (GORTEC). 
Bourhis J, Calais G, Lapeyre M, Tortochaux J, Alfonsi M, Sire C, Bardet E, Rives M, Bergerot P, Rhein B, Desprez B; French Head and Neck Cancer Group (GORTEC). 
Department of Radiation-Oncology, Gustave Roussy Institute, 39 rue Camille Desmoulins, 94805 Villejuif, France.


Curr Opin Oncol. - 2004 May

Altered fractionated radiotherapy in the management of head and neck carcinomas: advantages and limitations. 
Bourhis J, Etessami A, Wilbault P, Lusinchi A, Calais G, Lapeyre M, Pignon JP. 
Institut Gustave Roussy, Radiation Oncology & Statistic Departments, Villejuif, France.


Bull Cancer. - 2004 Feb

Docetaxel and squamous cell carcinoma of the head and neck
Calais G. 
Clinique d'oncologie et radiothérapie, Hôpital Bretonneau, 2, bd Tonnellé, 37044 Tours.


Int J Radiat Oncol Biol Phys. - 2004 Jan 1

Radiotherapy with concomitant weekly docetaxel for Stages III/IV oropharynx carcinoma. Results of the 98-02 GORTEC Phase II trial. 
Calais G, Bardet E, Sire C, Alfonsi M, Bourhis J, Rhein B, Tortochaux J, Man YT, Auvray H, Garaud P. 
Centre Hospitalier Universitaire, Tours, France


J Clin Oncol. - 2004 Jan 1

Final results of the 94-01 French Head and Neck Oncology and Radiotherapy Group randomized trial comparing radiotherapy alone with concomitant radiochemotherapy in advanced-stage oropharynx carcinoma. 

Denis F, Garaud P, Bardet E, Alfonsi M, Sire C, Germain T, Bergerot P, Rhein B, Tortochaux J, Calais G. 
Clinique d'Oncologie et Radiothérapie, Hôpital Bretonneau, 2 Blvd Tonnelé, 37044 Tours, France


Radiother Oncol - 2003 Dec

FCT-based delineation of lymp node levels and related CTVs in the node-negative neck : DAHANCA, EORTC, GORTEC, NCIC, RTOG concensus guidelines
Grégoire V, Levendag P, Ang KK, Bernier J, Braaksma M, Budach V, Chao C, Coche E, Cooper JS, Cosnard G, Eisbruch A, El-Sayed S, Emami B, Grau C, Hamoir M, Lee N, Maingon P, Muller K, Reychler H.

Radiation Oncology Dept. and Laboratory of Radiobiology, Université Catholique de Louvain, St-Luc University Hospital, B-1200 Brussels, Belgium.


Radiother Oncol - 2003 Dec

FLate toxicity results of the GORTEC 94-01 randomized trial comparing radiotherapy with concomitant radiochemotherapy for advanced-stage orophraynx carcinoma : comparison of LENT/SOMA, RTOG/EORTC, and NCI-CTC scoring systems.

Denis F, Garaud P, Bardet E, Alfonsi M, Sire C, Germain T, Bergerot P, Rhein B, Tortochaux J, Oudinot P, Calais G.

Clinique d'Oncologie et de Radiothérapie, Centre Hospitalier Universitaire, Tours, France


Semin Oncol. - 2002 Dec

Preliminary data of the GORTEC 2000-02 phase III trial comparing intravenous and subcutaneous administration of amifostine for head and neck tumors treated by external radiotherapy. 
Bardet E, Martin L, Calais G, Tuchais C, Bourhis J, Rhein B, Feham N, Alphonsi M. 
CRLCC Nantes Atlantique, Nantes, France.


Bull Cancer. - 2000 Aug

Stage III and IV cancers of the oropharynx: results of a randomized study of Gortec comparing radiotherapy alone with concomitant chemotherapy
Calais G, Alfonsi M, Bardet E, Sire C, Germain T, Bergerot P, Rhein B, Tortochaux J, Oudinot P, Bertrand P. 
Clinique d'oncologie et radiothérapie, Hôpital Bretonneau, Tours


J Natl Cancer Inst. - 1999 Dec 15

Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. 
Calais G, Alfonsi M, Bardet E, Sire C, Germain T, Bergerot P, Rhein B, Tortochaux J, Oudinot P, Bertrand P. 
G. Calais, Centre Hospitalier Universitaire Tours, France